Silk Protein for Your Eyes?

SilkTech Biopharmaceuticals is utilizing the natural therapeutic property of Silk Derived Proteins for use in eye drop products. Worldwide it is estimated that over 340MM people use eye drops annually, and in the US 15 million are currently using prescription products.

How It Works



Silk Protein for Your Eyes?

SilkTech Biopharmaceuticals is utilizing the natural therapeutic property of silk derived proteins for use in eye drop products. Worldwide it is estimated that over 340MM people use eye drops annually, and in the US 15 million are currently using prescription products.

How It Works

THE PRODUCT – SILK DERIVED PROTEIN


Silk derived protein is a novel ingredient that uses the natural properties of silk to enhance eye drop formulations. Silk derived protein enhances the spreading and wetting properties to improve eye drop formulation coating on the eye surface.  Silk derived protein can be used in both non-preserved and preserved preservation while being stored at room temperature for over two years.

MAINTAINING TEAR HEALTH IS IMPORTANT


Tear health is degraded by a variety of factors, including environment, pollution, lifestyle, demographics, age, and inflammatory diseases. For example, it is estimated that up to 340 million people suffer from Dry Eye Disease (DED) worldwide, with 45 - 60 million people in the US alone. Estimates show that nearly 16 million patients are diagnosed with DED in the US [1], and further studies suggest up to an additional 30 – 40 million individuals may remain undiagnosed and could benefit from therapeutic treatment [2]. Recent evidence suggests the magnitude of the problem is increasing over time [3].

Image

WORKING TO CREATE THE BEST EYE DROP


When compromised, the tear film may become unstable and/or leave portions of the ocular surface uncovered and non-wetting. This can be caused by a number of irritating effects, which may be environmental or physiological in nature. Silk Derived Protein is designed to enhance teardrop coating on the eye, and has been shown to provide symptom relief and promote tear health in clinical trials.

Image

ENHANCED TEAR COatING PROPERTIES


The spreading properties of saline vs. saline plus Silk Derived Protein can be demonstrated on a wax surface. Silk Derived Protein (1%) enhances eye drop coating upon eye drop application without increasing viscosity. This property is designed to improve coating on the ocular surface to enhance comfort without compromising vision quality.

Enhanced Adherence, Spreading & Wetting

Image
Surface Retention Angle
Image
Before Spreading
After Spreading

THE PRODUCT - SILK-DERIVED PROTEIN


Silk Derived Protein is a novel ingredient that uses the natural properties of silk to enhance eye drop formulations. Silk Derived Protein enhances the spreading and wetting properties to improve eye drop formulation coating on the eye surface.  Silk Derived Protein can be used in both non-preserved and preserved preservation while being stored at room temperature for over two years.

MAINTAINING TEAR HEALTH IS IMPORTANT


Tear health is degraded by a variety of factors, including environment, pollution, lifestyle, demographics, age, and inflammatory diseases. For example, it is estimated that up to 340 million people suffer from Dry Eye Disease (DED) worldwide, with 45 - 60 million people in the US alone. Estimates show that nearly 16 million patients are diagnosed with DED in the US [1], and further studies suggest up to an additional 30 – 40 million individuals may remain undiagnosed and could benefit from therapeutic treatment [2]. Recent evidence suggests the magnitude of the problem is increasing over time [3].

Image

WORKING TO CREATE THE BEST EYE DROP


When compromised, the tear film may become unstable and/or leave portions of the ocular surface uncovered and non-wetting. This can be caused by a number of irritating effects, which may be environmental or physiological in nature. Silk Derived Protein is designed to enhance teardrop coating on the eye, and has been shown to provide symptom relief and promote tear health in clinical trials.

Image

Enhanced Tear COATING PROPERTIES


The spreading properties of saline vs. saline plus Silk Derived Protein can be demonstrated on a wax surface. Silk Derived Protein (1%) enhances eye drop coding upon eye drop application without increasing viscosity. This property is designed to improve coating on the ocular surface to enhance comfort without compromising vision quality.

Enhanced Adherence, Spreading & Wetting

Image

Surface Retention Angle

Image

Before Spreading

After Spreading

More About Us